BMBF (ProINNO) Project 2007-2010 For a collaboration with a small company, Eco Luft- und Raumqualität, Cologne, a project was funded which deals with the identification of protein allergens in dust at the workplace.

25 Mio people suffer from allergies in Germany. Bakers allergy is an allergic skin irritation oreven asthma, which is caused by high-molecular compounds in flour, yeast or other components in the air of bakeries. It is recognized as an occupational disease. Infos

Based on the methods of proteomics, gel electrophoresis and mass spectrometry, in this project a web-based database will be built which will allow the screening of allergens at the workplace in order to improve prevention. 

Phosphorylation Analysis 

Promotion M. Zeller, 2004

S/T/Y-Phosphorylation 

Cooperation with: Zoology Osnabrück; Experimental Dermatology Münster; University of Warwick, UK; Biozentrum Basel, Schweiz

Zeller, M., T. Vogl, J. Roth, and S. König, Phosphorylation site analysis of MRP14 purified from granulocytes, Biomacromol. Mass Spectrom. 1, 2 (2006) in print

Zeller, M., Levkau, B., König, S., Protein Kinase B autophosphorylation affects activity. Biomacromol. Mass Spectrom. 1,3 (2007) in print

Zeller, M. and S. König, Impact of chromatography and mass spectrometry on the detection of protein phosphorylation sites. Anal. Bioanal. Chem. 378 (2004) 898-909 online Dec. 13, 2003; DOI: 10.1007/s00216-003-2391-2 Erratum DOI: 10.1007/s00216-004-2577-2

Zeller, M., F. Essmann, R..U. Jänicke, K.Schulze-Osthoff, and S. König, A rapid non-radioactive peptide phosphorylation assay. J. Exp. Therapeutics and Oncology 3 (2003) 1-3

Susanne Klumpp, Pharmaceutical and Medical Chemistry Münster 

Development of a method for the detection of nucleotide-growth factor complexes (2006; JASMS2008)